Frankfurters were surface inoculated with a 5-strain mixture of Listeria monocytogenes then treated with a pediocin (ALTATM 2341), post-packaging pasteurization with heat or post-packaging irradiation.All treatments effectively reduced L. monocytogenes numbers but combinations, particularly pediocin with heat or with irradiation were most effective for both reducing L. monocytogenes and suppressing growth of survivors. Pediocin and irradiation treatments were synergistic and achieved the greatest control of L. monocytogenes of all the treatments studied.These treatments offer meat processors alternatives to improve control of L. monocytogenes on processed meats.